Book on our site
Up to 10% cheaper
than Booking.com
Check rooms and rates
From159US$ /night
Check-in
16Mar2026Select date
Check-out
17Mar2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1240 Commerce Drive, Sikeston, Missouri, United States, MO 63801
-
Close to the Sikeston Depot Museum & Gallery
Great
8.2
8.7
/10
3.9
/5

Situated about 25 minutes' walk from the Sikeston Depot Museum & Gallery and 2.8 km from Hunter Memorial First Presbyterian Church, the smoke-free Hampton Inn Sikeston features a private art gallery. This 3-star inn provides Wi-Fi throughout the property as well as a banquet hall for collective gatherings.

Location

You'll need 41-minute drive to Cape Girardeau Regional airport. Malco Sikeston Cinema is a mere 400 metres away, and Memphis is 194 km from Hampton Inn Sikeston.

Also, a motorway is right off the hotel.

Rooms

The 91 rooms at this accommodation are equipped with comforts such as ironing facilities, as well as a flat-screen TV with satellite channels and a radio. They are decorated with elegant furniture.

Eat & Drink

Arby's serves American cuisine and is located in the vicinity of the Hampton Inn Sikeston.

Leisure & Business

A fitness studio and a heated swimming pool are available at this Sikeston hotel. Thanks to a golf club, guests can stay fit at the property. This hotel also features a xerox and safes for those arriving on business.

Must-do experiences

  • Savor a delicious meal at Lambert's Cafe for their signature rolls.
  • Visit the Sikeston Depot Museum for local history and artifacts.
  • Enjoy a sweet treat at the iconic Sikeston Candy Company.
  • Explore the unique shops in historic downtown Sikeston.
  • Check out the Sikeston Farmer's Market for fresh local produce.
View all

Select your room type

Hampton Inn Sikeston offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Studio Suite Non Smoking
2 persons
305 sq. feet 
1 King-size bed
Shower
King Room Accessible Tub Mobility Hearing Access or Non-Smoking
2 persons
305 sq. feet 
1 King-size bed
Shower
King Room Hearing Access or Non-Smoking
2 persons
305 sq. feet 
1 King-size bed
Shower
King Room
2 persons
305 sq. feet 
1 King-size bed
Shower
Click button to see more rooms
Show all rooms
Show all roomsLess

Price and Room Availability Calendar

Check availability and prices for your dates now!

Facilities

Hampton Inn Sikeston offers amenities for your comfortable stay and unforgettable experiences
Facilities: Great
8.4/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry

Dining

  • Snack bar

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Spa & Leisure

  • Indoor swimming pool

Room features

  • Air conditioning
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
Show more

Hampton Inn Sikeston Location

1240 Commerce Drive, Sikeston, Missouri, United States, MO 63801
Map view
1240 Commerce Drive, Sikeston, Missouri, United States, MO 63801
Nearby
Malco Sikeston Cinema
1400 ft
Restaurants
China Buffet Mongolian Grill
1600 ft
1207 S Main St
Arby's
2000 ft
1203 S Main St
Getting around
City Centre
Sikeston27 min  ·  1.4 mi
Airports
Cape Girardeau Regional Airport (CGI)76 min  ·  31.4 mi
Barkley Regional Airport (PAH)140 min  ·  57.6 mi
Interested in Nearby Hotel Rates?
Live prices. No outdated rates
Check Rates
Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
Wireless internet is available in for free.
Breakfast
All visitors are offered a buffet breakfast for a fee. 
Pets
Pets are allowed on request.
Number of floors:
4
Number of rooms:
91

Reviews and Ratings

Feedback about Hampton Inn Sikeston from previous guests about their experience.
Review score
Based on 110 verified reviews
8.4/10
Great
80%
Recommend
Breakfast
7.4/10
Cleanliness
8.4/10
Comfort
8.3/10
Facilities
8.4/10
Free Wi-Fi
8.3/10
Location
8.4/10
Staff
8.4/10
Value for money
7.8/10
Guest reviews
based on 83 reviews
8.2/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
Check-in
16Mar2026Select date
Check-out
17Mar2026Select date
Rooms and Guests2 Guests, 1 Room