Book on our site
Up to 10% cheaper
than Booking.com
Check rooms and rates
From119US$ /night
Check-in
29Jan2026Select date
Check-out
30Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4000 Market Street, Hannibal, Missouri, United States, 63401
-
Near Huckleberry Park
Very good
7.7
7.3
/10
3.3
3.3
/5

Situated 3.5 km from Rockcliffe Mansion and within a 10-minute drive of the historic prairie style public Riverview Park, the smoke-free Comfort Inn & Suites - Hannibal features a banquet hall for various purposes. This 2-star hotel also offers Wi-Fi in public areas, as well as a vending machine and a lift.

Location

You'll need 39-minute drive to Quincy Regional airport. The comfortable Comfort Inn & Suites is within reach of the 63-acre Huckleberry Park and 138 km from Maryland Heights.

Rooms

Furnished with a writing table and a sofa bed, some of the 74 rooms feature blackout drapes, an iron with ironing board, and air conditioning along with complimentary Wi-Fi and a flat screen TV. They offer couch beds in the bedrooms.

Leisure & Business

Comfort Inn & Suites - Hannibal offers a 24-hour fitness centre, spa therapy, a picnic area, and a golf course to diversify your leisure. Business and leisure travellers can also make use of a photocopier and complimentary wireless internet access.

Must-do experiences

  • Visit the Mark Twain Boyhood Home for a literary journey.
  • Savor a slice of the famous Maid-Rite sandwich at a local diner.
  • Explore the unique exhibits at the Hannibal History Museum.
  • Stroll along the Mississippi Riverfront for stunning sunset views.
  • Take a scenic riverboat cruise to see Hannibal from the water.
View all

Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Efficiency King Suite Non Smoking
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
King Suite Sofa Bed Non-Smoking
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
Air conditioning
Efficiency King Suite Sofa Bed Non-Smoking
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
Air conditioning
Queen Room Two Queen Beds Non-Smoking
2 persons
305 sq. feet 
2 King Size Beds
Air conditioning
Click button to see more rooms
Show all rooms
Show all roomsLess

Price and Room Availability Calendar

Check availability and prices for your dates now!

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Internet access
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Cycling
  • Bowling
  • Golf course
  • Fishing

Services

  • Housekeeping
  • Laundry

Dining

  • Picnic area/ Tables

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Indoor swimming pool
  • Sun loungers
  • Leisure/ TV room
  • Spa & wellness centre
  • Jacuzzi
  • Shallow end

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
Show more

Location

4000 Market Street, Hannibal, Missouri, United States, 63401
Map view
4000 Market Street, Hannibal, Missouri, United States, 63401
Nearby
Oakwood Christian Church
2500 ft
Prince Avenue Baptist Church
2900 ft
Church of Christ
3200 ft
Getting around
City Centre
Hannibal7 min  ·  2.8 mi
Airports
Quincy Regional Airport (UIN)74 min  ·  30.3 mi
Interested in Nearby Hotel Rates?
Live prices. No outdated rates
Check Rates
Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
High-speed internet access is available in for free.
Breakfast
A buffet breakfast is served and charges are applicable. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Year renovated:
2006
Number of rooms:
74
Former name
Holiday Inn Express Hotel And Suites Hannibal
Check-in
29Jan2026Select date
Check-out
30Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Need more options?
Check Top hotels near Comfort Inn & Suites - Hannibal
Days Inn By Wyndham Hannibal Exterior photo
Mobile-only price

Days Inn By Wyndham Hannibal

7.4
Very good102 reviews
14m from property
USD 44USD 39
per night
Hannibal Inn Hannibal Exterior photo
Mobile-only price

Hannibal Inn Hannibal

6.8
Nice67 reviews
127m from property
USD 56USD 50
per night
Baymont By Wyndham Hannibal Beds photo
Mobile-only price

Baymont By Wyndham Hannibal

6.7
Nice346 reviews
198m from property
USD 66USD 59
per night