Comfort Inn & Suites Chillicothe Exterior photoComfort Inn & Suites Chillicothe Exterior photoComfort Inn & Suites Chillicothe Exterior photo
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From109US$ /night
Check-in
03May2026Select date
Check-out
04May2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

250 Business 36, Chillicothe, Missouri, United States, 64601
-
Close to Chillicothe Main Street
Great
8.8
/10
4.6
/5

Comfort Inn & Suites Chillicothe, located a 20-minute walk from Chillicothe Community of Christ, features Wi-Fi in public areas. This hotel offers parking on site and an indoor swimming pool.

Location

The 3-star hotel is conveniently situated 2.3 km from Chillicothe Main Street. The property in Chillicothe is a 10-minute drive from Saint Columban Catholic Church.

This Chillicothe hotel offers a prime location near a forest. Sport lovers will enjoy the proximity of Green Hills Golf Course, which is 4.8 km away.

Also, a motorway is just off the Comfort Inn & Suites.

Eat & Drink

Serving American dishes, Applebee's is a 5-minute walk away.

Leisure & Business

This property offers options for sports and relaxation in a Jacuzzi and a sauna, or at a fitness club. The presence of a golf playground ensures guests an active stay at the Comfort Inn & Suites Chillicothe.

Must-do experiences

  • Visit the Adena Mansion & Gardens for rich local history.
  • Try the famous chili from the Chillicothe Chili Fest in the fall.
  • Check out the Ross County Historical Society for fascinating exhibits.
  • Stroll through Yoctangee Park for beautiful scenery and relaxation.
  • Don't miss the murals downtown that showcase our vibrant culture.
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Price and Room Availability Calendar

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Facilities

Comfort Inn & Suites Chillicothe offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Fire extinguishers

Sports & Fitness

  • Fitness centre
  • Hiking
  • Horseback riding
  • Tennis court
  • Bowling
  • Golf course

Guest Parking

  • Shared kitchen

Services

  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning

Business

  • Meeting/ Banquet facilities

Spa & Leisure

  • Indoor swimming pool
  • BBQ facilities
  • Leisure/ TV room
  • Spa & wellness centre
  • Sauna
  • Jacuzzi

Room features

  • Ironing facilities

Self-catering

  • Shared kitchen
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Comfort Inn & Suites Chillicothe Location

250 Business 36, Chillicothe, Missouri, United States, 64601
Map view
250 Business 36, Chillicothe, Missouri, United States, 64601
Nearby
Chillicothe Main Street
0 ft
Restaurants
China Garden
1900 ft
1023 S Washington St
McDonald's
2500 ft
810 Business Highway 36 West
Getting around
City Centre
Chillicothe30 min  ·  1.6 mi
Airports
Kirksville Regional (IRK)205 min  ·  84.7 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Private parking is possible on site for free.
Internet
Wireless internet is available in for free.
Breakfast
A buffet breakfast is served and charges are applicable. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of rooms:
72

Reviews and Ratings

Feedback about Comfort Inn & Suites Chillicothe from previous guests about their experience.
Review score
Based on 2 verified reviews
10.0/10
Perfect
100%
Recommend
Guest reviews
based on 45 reviews
8.8/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
Check-in
03May2026Select date
Check-out
04May2026Select date
Rooms and Guests2 Guests, 1 Room