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From98US$ /night
Check-in
29Jan2026Select date
Check-out
30Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

120 S Interstate Drive, Sikeston, Missouri, United States, 63801-8641
-
Near the Mississippi River
Very good
7.4
8.1
/10
3.8
3.6
/5

Nestled 6 km from the Sikeston Depot Museum & Gallery, Best Western Plus Sikeston hotel has a private art gallery. The hotel features both Wi-Fi in public areas and a car park on site.

Location

You'll need 35-minute drive to Cape Girardeau Regional airport. This 3-star hotel is also 10 minutes by car from the Malco Sikeston Cinema and Grill in Sikeston.

The Best Western is also in proximity to the Mississippi River.

Rooms

Some of the air-conditioned rooms feature a flat-screen TV with satellite channels and wireless internet as well as tea and coffee making facilities, and a microwave. Private bathrooms include nice touches such as dryers and bath sheets.

Leisure & Business

Guests can work out in a fitness studio or relax by a heated swimming pool. The presence of a golf club ensures guests an active stay at the Best Western Sikeston. A 24-hour business centre with a photocopier and complimentary wireless internet access are available for those travelling for business.

Must-do experiences

  • Taste the world-famous BBQ at Lambert's Cafe, a local favorite.
  • Visit the Sikeston Depot Museum for insights into local history.
  • Explore the town's unique Route 66 signs along the highway.
  • Grab a cone at the Sikeston Ice Cream Parlor for a sweet treat.
  • Catch a show at the local Delta Symphony Orchestra if you're in town.
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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Room Sofa Bed Non-Smoking
2 persons
325 sq. feet 
1 King-size bed and 1 Sofa bed
Shower
Coffee machine
King Room Non-Smoking
2 persons
240 sq. feet 
1 King-size bed
Coffee machine
Bathtub
King Room Roll Shower Disability Access or Non-Smoking
2 persons
240 sq. feet 
1 King-size bed
Shower
Coffee machine
Queen Room Two Queen Beds Non-Smoking
2 persons
240 sq. feet 
2 King Size Beds
Shower
Coffee machine
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Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Security
  • Lift
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Golf course

Services

  • Housekeeping
  • Laundry
  • Shops/Commercial services

Business

  • Business centre
  • Fax/Photocopying

Children

  • Children's buffet

Spa & Leisure

  • Indoor swimming pool
  • Sun loungers
  • Leisure/ TV room

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • AM/FM alarm clock
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Location

120 S Interstate Drive, Sikeston, Missouri, United States, 63801-8641
Map view
120 S Interstate Drive, Sikeston, Missouri, United States, 63801-8641
Restaurants
McDonald's
3100 ft
2605 E Malone
Getting around
City Centre
Sikeston9 min  ·  3.4 mi
Airports
Cape Girardeau Regional Airport (CGI)65 min  ·  26.7 mi
Barkley Regional Airport (PAH)131 min  ·  54.3 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Private parking is possible on site for free.
Internet
is available in for free.
Breakfast
All visitors are offered a american breakfast for a fee. 
Pets
Pets are allowed on request.
Number of rooms:
55
Former name
Holiday Inn Express
Check-in
29Jan2026Select date
Check-out
30Jan2026Select date
Rooms and Guests2 Guests, 1 Room
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